Sodium salicylate rewires hepatic metabolic pathways in obesity and attenuates IL-1β secretion from adipose tissue: The implications for obesity-impaired reverse cholesterol transport

INTRODUCTION: High-fat diet (HFD)-induced obesity impairs clearance of cholesterol through the Reverse Cholesterol Transport (RCT) pathway, with downregulation in hepatic expression of cholesterol and bile acid transporters, namely ABCG5/8 and ABCB11, and reduced high-density lipoprotein (HDL) chole...

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Detalles Bibliográficos
Autores principales: Kajani, Sarina, Curley, Sean, O'Reilly, Marcella E., Yin, Xiaofei, Dillon, Eugene T., Guo, Weili, Nilaweera, Kanishka N., Brennan, Lorraine, Roche, Helen M., McGillicuddy, Fiona C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762459/
https://www.ncbi.nlm.nih.gov/pubmed/34954383
http://dx.doi.org/10.1016/j.molmet.2021.101425

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