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Molecular species selectivity of lipid transport creates a mitochondrial sink for di‐unsaturated phospholipids
Mitochondria depend on the import of phospholipid precursors for the biosynthesis of phosphatidylethanolamine (PE) and cardiolipin, yet the mechanism of their transport remains elusive. A dynamic lipidomics approach revealed that mitochondria preferentially import di‐unsaturated phosphatidylserine (...
Autores principales: | Renne, Mike F, Bao, Xue, Hokken, Margriet WJ, Bierhuizen, Adolf S, Hermansson, Martin, Sprenger, Richard R, Ewing, Tom A, Ma, Xiao, Cox, Ruud C, Brouwers, Jos F, De Smet, Cedric H, Ejsing, Christer S, de Kroon, Anton IPM |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762554/ https://www.ncbi.nlm.nih.gov/pubmed/34873731 http://dx.doi.org/10.15252/embj.2020106837 |
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