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Molecular species selectivity of lipid transport creates a mitochondrial sink for di‐unsaturated phospholipids

Mitochondria depend on the import of phospholipid precursors for the biosynthesis of phosphatidylethanolamine (PE) and cardiolipin, yet the mechanism of their transport remains elusive. A dynamic lipidomics approach revealed that mitochondria preferentially import di‐unsaturated phosphatidylserine (...

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Detalles Bibliográficos
Autores principales: Renne, Mike F, Bao, Xue, Hokken, Margriet WJ, Bierhuizen, Adolf S, Hermansson, Martin, Sprenger, Richard R, Ewing, Tom A, Ma, Xiao, Cox, Ruud C, Brouwers, Jos F, De Smet, Cedric H, Ejsing, Christer S, de Kroon, Anton IPM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762554/
https://www.ncbi.nlm.nih.gov/pubmed/34873731
http://dx.doi.org/10.15252/embj.2020106837

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