NKG2D discriminates diverse ligands through selectively mechano‐regulated ligand conformational changes

Stimulatory immune receptor NKG2D binds diverse ligands to elicit differential anti‐tumor and anti‐virus immune responses. Two conflicting degeneracy recognition models based on static crystal structures and in‐solution binding affinities have been considered for almost two decades. Whether and how...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, Juan, Shi, Jiawei, Zhang, Yong, Liu, Junwei, An, Chenyi, Zhu, Huaying, Wu, Peng, Hu, Wei, Qin, Rui, Yao, Danmei, Shou, Xin, Xu, Yibing, Tong, Zhou, Wen, Xue, Xu, Jianpo, Zhang, Jin, Fang, Weijia, Lou, Jizhong, Yin, Weiwei, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762575/
https://www.ncbi.nlm.nih.gov/pubmed/34913508
http://dx.doi.org/10.15252/embj.2021107739

Ejemplares similares

Ejemplares similares