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scAnnotatR: framework to accurately classify cell types in single-cell RNA-sequencing data

BACKGROUND: Automatic cell type identification is essential to alleviate a key bottleneck in scRNA-seq data analysis. While most existing classification tools show good sensitivity and specificity, they often fail to adequately not-classify cells that are missing in the used reference. Additionally,...

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Detalles Bibliográficos
Autores principales: Nguyen, Vy, Griss, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762856/
https://www.ncbi.nlm.nih.gov/pubmed/35038984
http://dx.doi.org/10.1186/s12859-022-04574-5

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