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Paediatric lung injury due to accidental ingestion of meperfluthrin: a case report

BACKGROUND: It is common for children to accidentally ingest chemical drugs with different degrees of toxicity. Meperfluthrin is a highly effective and easy-to-use pyrethroid pesticide with low toxicity. It is widely used in electric mosquito coils. This type of electric mosquito coil is used in dai...

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Autores principales: Li, Zhongqiang, Wu, Xuejun, Lv, Gaomei, Ren, Zhijuan, Yang, Huimin, Xu, Leilei, Guan, Qingli, Meng, Xiuqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762887/
https://www.ncbi.nlm.nih.gov/pubmed/35038988
http://dx.doi.org/10.1186/s12887-022-03117-4
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author Li, Zhongqiang
Wu, Xuejun
Lv, Gaomei
Ren, Zhijuan
Yang, Huimin
Xu, Leilei
Guan, Qingli
Meng, Xiuqi
author_facet Li, Zhongqiang
Wu, Xuejun
Lv, Gaomei
Ren, Zhijuan
Yang, Huimin
Xu, Leilei
Guan, Qingli
Meng, Xiuqi
author_sort Li, Zhongqiang
collection PubMed
description BACKGROUND: It is common for children to accidentally ingest chemical drugs with different degrees of toxicity. Meperfluthrin is a highly effective and easy-to-use pyrethroid pesticide with low toxicity. It is widely used in electric mosquito coils. This type of electric mosquito coil is used in daily life, which increases the chance of exposure among children and, consequently, may lead to accidental ingestion. There are only few reports of meperfluthrin poisoning causing lung injury in children. We report a rare clinical case of lung injury wherein a child ingested meperfluthrin orally. CASE PRESENTATION: We report the case of a 1-year-old boy who accidentally swallowed an electric mosquito coil containing meperfluthrin and developed cough and fever. The patient’s parents observed him swallowing the electric mosquito coil (Qiangshou®). Although he was stopped, the child had already swallowed approximately 10 ml of the liquid. According to the instructions, it contained 9 mg/ml of meperfluthrin, thus, it was assumed that he ingested meperfluthrin at a dose of approximately 90 mg. Computed tomography (CT) of his lungs showed uneven brightness in both lungs with multiple spots, scaly shadows, and mesh. Density of the shadows indicated lung parenchymal and interstitial lung disease. Lung tidal function tests indicated obstructive ventilation dysfunction. After evaluation and treatment, his cough drastically reduced, his fever disappeared, and his lung CT findings showed improvement. Therefore, accidental ingestion of meperfluthrin led to acute lung injury in a paediatric patient. Because of prompt treatment, his lung lesions recovered well. CONCLUSIONS: Meperfluthrin causes airway mucosal damage and hypersensitivity. Lung CT and lung tidal function measurements can be used to monitor changes in the condition. Presently, there is a lack of specific detoxification drugs for meperfluthrin poisoning. Thus, the focus of treatment is to protect the airway mucosa and reduce inflammatory reactions.
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spelling pubmed-87628872022-01-18 Paediatric lung injury due to accidental ingestion of meperfluthrin: a case report Li, Zhongqiang Wu, Xuejun Lv, Gaomei Ren, Zhijuan Yang, Huimin Xu, Leilei Guan, Qingli Meng, Xiuqi BMC Pediatr Case Report BACKGROUND: It is common for children to accidentally ingest chemical drugs with different degrees of toxicity. Meperfluthrin is a highly effective and easy-to-use pyrethroid pesticide with low toxicity. It is widely used in electric mosquito coils. This type of electric mosquito coil is used in daily life, which increases the chance of exposure among children and, consequently, may lead to accidental ingestion. There are only few reports of meperfluthrin poisoning causing lung injury in children. We report a rare clinical case of lung injury wherein a child ingested meperfluthrin orally. CASE PRESENTATION: We report the case of a 1-year-old boy who accidentally swallowed an electric mosquito coil containing meperfluthrin and developed cough and fever. The patient’s parents observed him swallowing the electric mosquito coil (Qiangshou®). Although he was stopped, the child had already swallowed approximately 10 ml of the liquid. According to the instructions, it contained 9 mg/ml of meperfluthrin, thus, it was assumed that he ingested meperfluthrin at a dose of approximately 90 mg. Computed tomography (CT) of his lungs showed uneven brightness in both lungs with multiple spots, scaly shadows, and mesh. Density of the shadows indicated lung parenchymal and interstitial lung disease. Lung tidal function tests indicated obstructive ventilation dysfunction. After evaluation and treatment, his cough drastically reduced, his fever disappeared, and his lung CT findings showed improvement. Therefore, accidental ingestion of meperfluthrin led to acute lung injury in a paediatric patient. Because of prompt treatment, his lung lesions recovered well. CONCLUSIONS: Meperfluthrin causes airway mucosal damage and hypersensitivity. Lung CT and lung tidal function measurements can be used to monitor changes in the condition. Presently, there is a lack of specific detoxification drugs for meperfluthrin poisoning. Thus, the focus of treatment is to protect the airway mucosa and reduce inflammatory reactions. BioMed Central 2022-01-17 /pmc/articles/PMC8762887/ /pubmed/35038988 http://dx.doi.org/10.1186/s12887-022-03117-4 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Li, Zhongqiang
Wu, Xuejun
Lv, Gaomei
Ren, Zhijuan
Yang, Huimin
Xu, Leilei
Guan, Qingli
Meng, Xiuqi
Paediatric lung injury due to accidental ingestion of meperfluthrin: a case report
title Paediatric lung injury due to accidental ingestion of meperfluthrin: a case report
title_full Paediatric lung injury due to accidental ingestion of meperfluthrin: a case report
title_fullStr Paediatric lung injury due to accidental ingestion of meperfluthrin: a case report
title_full_unstemmed Paediatric lung injury due to accidental ingestion of meperfluthrin: a case report
title_short Paediatric lung injury due to accidental ingestion of meperfluthrin: a case report
title_sort paediatric lung injury due to accidental ingestion of meperfluthrin: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762887/
https://www.ncbi.nlm.nih.gov/pubmed/35038988
http://dx.doi.org/10.1186/s12887-022-03117-4
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