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Fibrotic alterations in human annulus fibrosus correlate with progression of intervertebral disc herniation
BACKGROUND: Intervertebral disc (IVD) herniation is characterized by annulus fibrosus failure (AF) in containing the nucleus pulposus (NP). IVD herniation involves cellular and extracellular matrix (ECM) alterations that have been associated with tissue fibrosis, although still poorly investigated....
Autores principales: | Castro, A. L., Ribeiro-Machado, C., Oliveira, C. M., Teixeira, G. Q., Neidlinger-Wilke, C., Pereira, P., Vaz, R., Barbosa, M. A., Gonçalves, R. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762926/ https://www.ncbi.nlm.nih.gov/pubmed/35039075 http://dx.doi.org/10.1186/s13075-021-02690-w |
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