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SNORA23 inhibits HCC tumorigenesis by impairing the 2′-O-ribose methylation level of 28S rRNA

OBJECTIVE: The dysregulation of ribosome biogenesis is associated with the progression of numerous tumors, including hepatocellular carcinoma (HCC). Small nucleolar RNAs (snoRNAs) regulate ribosome biogenesis by guiding the modification of ribosomal RNAs (rRNAs). However, the underlying mechanism of...

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Detalles Bibliográficos
Autores principales: Liu, Zhiyong, Pang, Yanan, Jia, Yin, Qin, Qin, Wang, Rui, Li, Wei, Jing, Jie, Liu, Haidong, Liu, Shanrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763008/
https://www.ncbi.nlm.nih.gov/pubmed/33710804
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0343