Highly rigid H3.1/H3.2–H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells

The placenta is a highly evolved, specialized organ in mammals. It differs from other organs in that it functions only for fetal maintenance during gestation. Therefore, there must be intrinsic mechanisms that guarantee its unique functions. To address this question, we comprehensively analyzed epig...

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Detalles Bibliográficos
Autores principales: Hada, Masashi, Miura, Hisashi, Tanigawa, Akie, Matoba, Shogo, Inoue, Kimiko, Ogonuki, Narumi, Hirose, Michiko, Watanabe, Naomi, Nakato, Ryuichiro, Fujiki, Katsunori, Hasegawa, Ayumi, Sakashita, Akihiko, Okae, Hiroaki, Miura, Kento, Shikata, Daiki, Arima, Takahiro, Shirahige, Katsuhiko, Hiratani, Ichiro, Ogura, Atsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763053/
https://www.ncbi.nlm.nih.gov/pubmed/34992147
http://dx.doi.org/10.1101/gad.348782.121

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