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Transcription factor-mediated intestinal metaplasia and the role of a shadow enhancer

Barrett's esophagus (BE) and gastric intestinal metaplasia are related premalignant conditions in which areas of human stomach epithelium express mixed gastric and intestinal features. Intestinal transcription factors (TFs) are expressed in both conditions, with unclear causal roles and cis-reg...

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Detalles Bibliográficos
Autores principales: Singh, Harshabad, Seruggia, Davide, Madha, Shariq, Saxena, Madhurima, Nagaraja, Ankur K., Wu, Zhong, Zhou, Jin, Huebner, Aaron J., Maglieri, Adrianna, Wezenbeek, Juliette, Hochedlinger, Konrad, Orkin, Stuart H., Bass, Adam J., Hornick, Jason L., Shivdasani, Ramesh A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763054/
https://www.ncbi.nlm.nih.gov/pubmed/34969824
http://dx.doi.org/10.1101/gad.348983.121