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Astragaloside IV Ameliorates Streptozotocin Induced Pancreatic β-Cell Apoptosis and Dysfunction Through SIRT1/P53 and Akt/GSK3β/Nrf2 Signaling Pathways

BACKGROUND: Absolute or relative lack of insulin secretion caused by pancreatic β-cell dysfunction can lead to diabetes. Astragaloside IV (AS-IV), the main components of the traditional Chinese medicine Astragalus, has anti-oxidant, anti-inflammatory and anti-apoptotic properties, and exerts anti-di...

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Detalles Bibliográficos
Autores principales:	Lin, Yuqiong, Xu, Ying, Zheng, Xin, Zhang, Jingwen, Liu, Junfeng, Wu, Guotu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763261/ https://www.ncbi.nlm.nih.gov/pubmed/35046684 http://dx.doi.org/10.2147/DMSO.S347650

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