Novel Quinolone Derivatives: Synthesis and Antioxidant Activity

Novel quinolone derivatives have been designed and readily synthesized according to a simple protocol including O-alkylation and Claisen rearrangement processes. Structures of the synthesized compounds have been confirmed by IR, (1)H and (13)C NMR, and mass spectra. The new products have been tested...

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Autores principales: Prasad, Mutyala Veera Venkata Vara, Rao, Radha Hunasenahalli Raghavendra, Veeranna, Vadde, Chennupalli, Venkata Suryanarayana, Sathish, Byrappa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763360/
https://www.ncbi.nlm.nih.gov/pubmed/35068916
http://dx.doi.org/10.1134/S1070363221120239
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author Prasad, Mutyala Veera Venkata Vara
Rao, Radha Hunasenahalli Raghavendra
Veeranna, Vadde
Chennupalli, Venkata Suryanarayana
Sathish, Byrappa
author_facet Prasad, Mutyala Veera Venkata Vara
Rao, Radha Hunasenahalli Raghavendra
Veeranna, Vadde
Chennupalli, Venkata Suryanarayana
Sathish, Byrappa
author_sort Prasad, Mutyala Veera Venkata Vara
collection PubMed
description Novel quinolone derivatives have been designed and readily synthesized according to a simple protocol including O-alkylation and Claisen rearrangement processes. Structures of the synthesized compounds have been confirmed by IR, (1)H and (13)C NMR, and mass spectra. The new products have been tested for their antioxidant activity, and two of those demonstrate high antioxidant activity.
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spelling pubmed-87633602022-01-18 Novel Quinolone Derivatives: Synthesis and Antioxidant Activity Prasad, Mutyala Veera Venkata Vara Rao, Radha Hunasenahalli Raghavendra Veeranna, Vadde Chennupalli, Venkata Suryanarayana Sathish, Byrappa Russ J Gen Chem Article Novel quinolone derivatives have been designed and readily synthesized according to a simple protocol including O-alkylation and Claisen rearrangement processes. Structures of the synthesized compounds have been confirmed by IR, (1)H and (13)C NMR, and mass spectra. The new products have been tested for their antioxidant activity, and two of those demonstrate high antioxidant activity. Pleiades Publishing 2022-01-17 2021 /pmc/articles/PMC8763360/ /pubmed/35068916 http://dx.doi.org/10.1134/S1070363221120239 Text en © Pleiades Publishing, Ltd. 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Prasad, Mutyala Veera Venkata Vara
Rao, Radha Hunasenahalli Raghavendra
Veeranna, Vadde
Chennupalli, Venkata Suryanarayana
Sathish, Byrappa
Novel Quinolone Derivatives: Synthesis and Antioxidant Activity
title Novel Quinolone Derivatives: Synthesis and Antioxidant Activity
title_full Novel Quinolone Derivatives: Synthesis and Antioxidant Activity
title_fullStr Novel Quinolone Derivatives: Synthesis and Antioxidant Activity
title_full_unstemmed Novel Quinolone Derivatives: Synthesis and Antioxidant Activity
title_short Novel Quinolone Derivatives: Synthesis and Antioxidant Activity
title_sort novel quinolone derivatives: synthesis and antioxidant activity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763360/
https://www.ncbi.nlm.nih.gov/pubmed/35068916
http://dx.doi.org/10.1134/S1070363221120239
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