Protective Effects of Astragaloside IV on Uric Acid-Induced Pancreatic β-Cell Injury through PI3K/AKT Pathway Activation

BACKGROUND: Elevated uric acid (UA) has been found to damage pancreatic β-cell, promote oxidative stress, and cause insulin resistance in type 2 diabetes (T2D). Astragaloside IV (AS-IV), a major active monomer extracted from Astragalus membranaceus (Fisch.) Bunge. which belongs to TRIB. Galegeae (Br...

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Detalles Bibliográficos
Autores principales: Jiang, Zhenhuan, Wang, Gang, Meng, Lingling, Tang, Yunzhao, Yang, Min, Ni, Changlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763508/
https://www.ncbi.nlm.nih.gov/pubmed/35047042
http://dx.doi.org/10.1155/2022/2429162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763508/
https://www.ncbi.nlm.nih.gov/pubmed/35047042
http://dx.doi.org/10.1155/2022/2429162

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