Cargando…

Quanzhenyiqitang Reverses LPS-Induced Inflammation via Inhibiting PYK2/p38MAPK/HDAC2/CK2 Signaling Pathway in Rat Alveolar Macrophage

Chronic obstructive pulmonary disease (COPD) is a common chronic pulmonary disease with multiple etiologies and pathological changes. PYK2 expression is significantly increased in lipopolysaccharide-induced lung injury, but it mediates chronic lung inflammation. The mechanism of its occurrence remai...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Ke-Qiang, Li, Da-zhi, Chen, Zhi-bin, Zhang, Chuan-lin, Wang, Bin-can, Wang, Chun-e
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763520/ https://www.ncbi.nlm.nih.gov/pubmed/35047050 http://dx.doi.org/10.1155/2022/7857022

Ejemplares similares

Effect of Quanzhenyiqitang on apoptosis of alveolar macrophages and expression of histone deacetylase 2 in rats with chronic obstructive pulmonary disease
por: LI, DA-ZHI, et al.
Publicado: (2014)

Pyk2 for perfect bones
por: LeBrasseur, Nicole
Publicado: (2007)

Role of Pyk2 in Human Cancers
por: Shen, Ting, et al.
Publicado: (2018)

Pyk2/MCU Pathway as a New Target for Reversing Atherosclerosis
por: Zhang, Yingzhen, et al.
Publicado: (2021)

PIWIL2 suppresses Siah2-mediated degradation of HDAC3 and facilitates CK2α-mediated HDAC3 phosphorylation
por: Zhang, Yingying, et al.
Publicado: (2018)

Pyk2 promotes tumor progression in renal cell carcinoma
por: Zhao, Tangliang, et al.
Publicado: (2018)

Inhibition of LPS-Induced Activation of Coagulation by p38 MAPK Inhibitor
por: Koch, Lutz, et al.
Publicado: (2012)

Novel Role of Src in Priming Pyk2 Phosphorylation
por: Zhao, Ming, et al.
Publicado: (2016)

Convergent Effects of Resveratrol and PYK2 on Prostate Cells
por: Conte, Andrea, et al.
Publicado: (2016)

PYK2 at the Intersection of Signaling Pathways in Pancreatic Cancer
por: Means, Anna L.
Publicado: (2019)

PYK2 promotes HER2-positive breast cancer invasion
por: Al-Juboori, Shaymaa IK., et al.
Publicado: (2019)

Pyk2 regulates sepsis-induced lung injury via ferroptosis
por: Wang, Jia, et al.
Publicado: (2023)

Hematopoietic Pyk2 regulates migration of differentiated HL-60 cells
por: Wang, Lin, et al.
Publicado: (2010)

Hypertrophic differentiation of mesenchymal stem cells is suppressed by xanthotoxin via the p38-MAPK/HDAC4 pathway
por: Cao, Zhen, et al.
Publicado: (2017)

High expression of PYK2 is associated with poor prognosis and cancer progression in early-stage cervical carcinoma
por: Zhang, Can, et al.
Publicado: (2022)

Suppression of Pyk2 Kinase and Cellular Activities by Fip200
por: Ueda, Hiroki, et al.
Publicado: (2000)

Pyk2 Regulates MAMs and Mitochondrial Dynamics in Hippocampal Neurons
por: López-Molina, Laura, et al.
Publicado: (2022)

Tyrosine 402 Phosphorylation of Pyk2 Is Involved in Ionomycin-Induced Neurotransmitter Release
por: Zhang, Zhao, et al.
Publicado: (2014)

Microglial p38α MAPK is critical for LPS-induced neuron degeneration, through a mechanism involving TNFα
por: Xing, Bin, et al.
Publicado: (2011)

Inhibition of HDAC6 alleviating lipopolysaccharide-induced p38MAPK phosphorylation and neuroinflammation in mice
por: Song, Yuanjian, et al.
Publicado: (2019)

Exogenous carbon monoxide inhibits neutrophil infiltration in LPS-induced sepsis by interfering with FPR1 via p38 MAPK but not GRK2
por: Wang, Xu, et al.
Publicado: (2016)

CK2 Phosphorylating I(2)(PP2A)/SET Mediates Tau Pathology and Cognitive Impairment
por: Zhang, Qing, et al.
Publicado: (2018)

MKP-3 suppresses LPS-induced inflammatory responses in HUVECs via inhibition of p38 MAPK/NF-κB pathway
por: Unenkhuu, Banzragchgarav, et al.
Publicado: (2021)

GBE50 Attenuates Inflammatory Response by Inhibiting the p38 MAPK and NF-κB Pathways in LPS-Stimulated Microglial Cells
por: He, Gai-ying, et al.
Publicado: (2014)

Impact of the Whole Genome Duplication Event on PYK Activity and Effects of a PYK1 Mutation on Metabolism in S. cerevisiae
por: Chen, Hong, et al.
Publicado: (2021)

The Multiple Personalities of the Regulatory Subunit of Protein Kinase CK2: CK2 Dependent and CK2 Independent Roles Reveal a Secret Identity for CK2β
por: Bibby, Ashley C., et al.
Publicado: (2005)

Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development
por: Naser, Rayan, et al.
Publicado: (2018)

Non-redundant functions of FAK and Pyk2 in intestinal epithelial repair
por: Thomas, Keena S., et al.
Publicado: (2019)

Pyk2 regulates cell-edge protrusion dynamics by interacting with Crk
por: Lukic, Nikola, et al.
Publicado: (2021)

Pyk2 suppresses contextual fear memory in an autophosphorylation-independent manner
por: Zheng, Jin, et al.
Publicado: (2021)

Histone deacetylase 2 (HDAC2) attenuates lipopolysaccharide (LPS)-induced inflammation by regulating PAI-1 expression
por: Fang, Wen-Feng, et al.
Publicado: (2018)

Oral and inhaled p38 MAPK inhibitors: effects on inhaled LPS challenge in healthy subjects
por: Singh, Dave, et al.
Publicado: (2015)

Role of p38 MAPK and STAT3 in lipopolysaccharide-stimulated mouse alveolar macrophages
por: MENG, AIHONG, et al.
Publicado: (2014)

Pyruvate Kinase M2 Contributes to TLR-Mediated Inflammation and Autoimmunity by Promoting Pyk2 Activation
por: Zhang, Xin, et al.
Publicado: (2021)

PYK2 mediates the BRAF inhibitor (vermurafenib)-induced invadopodia formation and metastasis in melanomas
por: Shen, Junling, et al.
Publicado: (2022)

The significance of proline-rich tyrosine kinase2 (Pyk2) on hepatocellular carcinoma progression and recurrence
por: Sun, C K, et al.
Publicado: (2007)

The Role of Proline Rich Tyrosine Kinase 2 (Pyk2) on Cisplatin Resistance in Hepatocellular Carcinoma
por: Geng, Wei, et al.
Publicado: (2011)

Tyrosine Phosphorylation of Pyk2 Is Selectively Regulated by Fyn During TCR Signaling
por: Qian, Dapeng, et al.
Publicado: (1997)

PYK2 negatively regulates the Hippo pathway in TNBC by stabilizing TAZ protein
por: Kedan, Amir, et al.
Publicado: (2018)

CD56 regulates human NK cell cytotoxicity through Pyk2
por: Gunesch, Justin T, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_iugvpgh6nr9mbcup7t2s7mpmih