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TPMT、NUDT15基因多态性对成人急性淋巴细胞白血病患者6-巯基嘌呤耐受性的影响
OBJECTIVE: To investigate the effect of genetic polymorphisms of TPMT*2 rs1800462, TPMT*3B rs1800460, TPMT*3C rs1142345, and NUDT15 rs116855232 on the tolerance of 6-mercaptopurine (6-MP) therapy in adult acute lymphoblastic leukemia (ALL). METHODS: A total of 216 adult patients who were diagnosed w...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Editorial office of Chinese Journal of Hematology
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763585/ https://www.ncbi.nlm.nih.gov/pubmed/35045652 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2021.11.005 |