Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis

Molecular profiling of single cells has advanced our knowledge of the molecular basis of development. However, current approaches mostly rely on dissociating cells from tissues, thereby losing the crucial spatial context of regulatory processes. Here, we apply an image-based single-cell transcriptom...

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Detalles Bibliográficos
Autores principales: Lohoff, T., Ghazanfar, S., Missarova, A., Koulena, N., Pierson, N., Griffiths, J. A., Bardot, E. S., Eng, C.-H. L., Tyser, R. C. V., Argelaguet, R., Guibentif, C., Srinivas, S., Briscoe, J., Simons, B. D., Hadjantonakis, A.-K., Göttgens, B., Reik, W., Nichols, J., Cai, L., Marioni, J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763645/
https://www.ncbi.nlm.nih.gov/pubmed/34489600
http://dx.doi.org/10.1038/s41587-021-01006-2

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