Novel CTRP8‐RXFP1‐JAK3‐STAT3 axis promotes Cdc42‐dependent actin remodeling for enhanced filopodia formation and motility in human glioblastoma cells

C1q tumor necrosis factor‐related peptide 8 (CTRP8) is the least studied member of the C1Q‐TNF‐related peptide family. We identified CTRP8 as a ligand of the G protein‐coupled receptor relaxin family peptide receptor 1 (RXFP1) in glioblastoma multiforme (GBM). The CTRP8‐RXFP1 ligand–receptor system...

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Detalles Bibliográficos
Autores principales: Glogowska, Aleksandra, Thanasupawat, Thatchawan, Beiko, Jason, Pitz, Marshall, Hombach‐Klonisch, Sabine, Klonisch, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763656/
https://www.ncbi.nlm.nih.gov/pubmed/33960104
http://dx.doi.org/10.1002/1878-0261.12981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763656/
https://www.ncbi.nlm.nih.gov/pubmed/33960104
http://dx.doi.org/10.1002/1878-0261.12981

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