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Hedgehog−Gli2 Signaling Promotes Chemoresistance in Ovarian Cancer Cells by Regulating MDR1

BACKGROUND: Cisplatin (DDP) resistance remains a key challenge in improving the clinical outcome of patients with ovarian cancer (OC). Gli2 overexpression can lead to DDP resistance in OC cells, but the specific underlying regulatory mechanism remains unclear. The membrane transporter encoding gene...

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Detalles Bibliográficos
Autores principales:	Wang, Qian, Wei, Xin, Hu, Lanyan, Zhuang, Lingling, Zhang, Hong, Chen, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763667/ https://www.ncbi.nlm.nih.gov/pubmed/35059317 http://dx.doi.org/10.3389/fonc.2021.794959

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