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Use of Physiologically-Based Kinetics Modelling to Reliably Predict Internal Concentrations of the UV Filter, Homosalate, After Repeated Oral and Topical Application

Ethical and legal considerations have led to increased use of non-animal methods to evaluate the safety of chemicals for human use. We describe the development and qualification of a physiologically-based kinetics (PBK) model for the cosmetic UV filter ingredient, homosalate, to support its safety w...

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Detalles Bibliográficos
Autores principales:	Najjar, Abdulkarim, Schepky, Andreas, Krueger, Christopher-Tilman, Dent, Matthew, Cable, Sophie, Li, Hequn, Grégoire, Sebastien, Roussel, Laurene, Noel-Voisin, Audrey, Hewitt, Nicola J., Cardamone, Estefania
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763688/ https://www.ncbi.nlm.nih.gov/pubmed/35058784 http://dx.doi.org/10.3389/fphar.2021.802514

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