The Role of NF-kB in the Downregulation of Organic Cation Transporter 2 Expression and Renal Cation Secretion in Kidney Disease

Organic cation transporter 2 (OCT2), encoded by the SLC22A2 gene, is the main cation transporter on the basolateral membrane of proximal tubular cells. OCT2 facilitates the entry step of the vectorial transport of most cations from the peritubular space into the urine. OCT2 downregulation in kidney...

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Detalles Bibliográficos
Autores principales: Han, Chao, Zheng, Juan, Wang, Fengyi, Lu, Qingyang, Chen, Qingfa, Hu, Ankang, Visentin, Michele, Kullak-Ublick, Gerd A., Gai, Zhibo, Chu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763702/
https://www.ncbi.nlm.nih.gov/pubmed/35059420
http://dx.doi.org/10.3389/fmed.2021.800421

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