Cargando…
Molecular Basis of Coupled Transport and Anion Conduction in Excitatory Amino Acid Transporters
Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system. After its release from presynaptic nerve terminals, glutamate is quickly removed from the synaptic cleft by excitatory amino acid transporters (EAATs) 1–5, a subfamily of glutamate transporters. The five prot...
Autores principales: | Alleva, Claudia, Machtens, Jan-Philipp, Kortzak, Daniel, Weyand, Ingo, Fahlke, Christoph |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763778/ https://www.ncbi.nlm.nih.gov/pubmed/33587237 http://dx.doi.org/10.1007/s11064-021-03252-x |
Ejemplares similares
-
Allosteric gate modulation confers K(+) coupling in glutamate transporters
por: Kortzak, Daniel, et al.
Publicado: (2019) -
Apo state pore opening as functional basis of increased EAAT anion channel activity in episodic ataxia 6
por: Suslova, Mariia, et al.
Publicado: (2023) -
Vesicular glutamate transporters are H(+)-anion exchangers that operate at variable stoichiometry
por: Kolen, Bettina, et al.
Publicado: (2023) -
Excitatory Amino Acid Transporter EAAT5 Improves Temporal Resolution in the Retina
por: Gehlen, Jana, et al.
Publicado: (2021) -
Na(+)-dependent gate dynamics and electrostatic attraction ensure substrate coupling in glutamate transporters
por: Alleva, C., et al.
Publicado: (2020)