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Pharmacokinetic/Pharmacodynamic Based Breakpoints of Polymyxin B for Bloodstream Infections Caused by Multidrug-Resistant Gram-Negative Pathogens

The latest PK/PD findings have demonstrated negligible efficacy of intravenous polymyxins against pulmonary infections. We investigated pharmacokinetic/pharmacodynamic (PK/PD)-based breakpoints of polymyxin B for bloodstream infections and the rationality of the recent withdrawal of polymyxin suscep...

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Detalles Bibliográficos
Autores principales:	Bian, Xingchen, Liu, Xiaofen, Hu, Fupin, Feng, Meiqing, Chen, Yuancheng, Bergen, Phillip J., Li, Jian, Li, Xin, Guo, Yan, Zhang, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763792/ https://www.ncbi.nlm.nih.gov/pubmed/35058776 http://dx.doi.org/10.3389/fphar.2021.785893

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