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Gut-Microbiome Composition in Response to Phenylketonuria Depends on Dietary Phenylalanine in BTBR Pah(enu2) Mice

Phenylketonuria (PKU) is a metabolic disorder caused by a hepatic enzyme deficiency causing high blood and brain levels of the amino acid Phenylalanine (Phe), leading to severe cognitive and psychological deficits that can be prevented, but not completely, by dietary treatment. The behavioral outcom...

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Detalles Bibliográficos
Autores principales: van der Goot, Els, Vink, Stefanie N., van Vliet, Danique, van Spronsen, Francjan J., Falcao Salles, Joana, van der Zee, Eddy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763796/
https://www.ncbi.nlm.nih.gov/pubmed/35059423
http://dx.doi.org/10.3389/fnut.2021.735366