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Cost-Effectiveness of Public Health Measures to Control COVID-19 in China: A Microsimulation Modeling Study
This study aimed to assess the cost-effectiveness of various public health measures in dealing with coronavirus disease 2019 (COVID-19) in China. A stochastic agent-based model was used to simulate the progress of the COVID-19 outbreak in scenario I (imported one case) and scenario II (imported four...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763804/ https://www.ncbi.nlm.nih.gov/pubmed/35059369 http://dx.doi.org/10.3389/fpubh.2021.726690 |
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author | Wang, Qiang Shi, Naiyang Huang, Jinxin Yang, Liuqing Cui, Tingting Ai, Jing Ji, Hong Xu, Ke Ahmad, Tauseef Bao, Changjun Jin, Hui |
author_facet | Wang, Qiang Shi, Naiyang Huang, Jinxin Yang, Liuqing Cui, Tingting Ai, Jing Ji, Hong Xu, Ke Ahmad, Tauseef Bao, Changjun Jin, Hui |
author_sort | Wang, Qiang |
collection | PubMed |
description | This study aimed to assess the cost-effectiveness of various public health measures in dealing with coronavirus disease 2019 (COVID-19) in China. A stochastic agent-based model was used to simulate the progress of the COVID-19 outbreak in scenario I (imported one case) and scenario II (imported four cases) with a series of public health measures. The main outcomes included the avoided infections and incremental cost-effectiveness ratios (ICERs). Sensitivity analyses were performed to assess uncertainty. The results indicated that isolation-and-quarantine averted the COVID-19 outbreak at the lowest ICERs. The joint strategy of personal protection and isolation-and-quarantine averted one more case than only isolation-and-quarantine with additional costs. The effectiveness of isolation-and-quarantine decreased with lowering quarantine probability and increasing delay time. The strategy that included community containment would be cost-effective when the number of imported cases was >65, or the delay time of the quarantine was more than 5 days, or the quarantine probability was below 25%, based on current assumptions. In conclusion, isolation-and-quarantine was the most cost-effective intervention. However, personal protection combined with isolation-and-quarantine was the optimal strategy for averting more cases. The community containment could be more cost-effective as the efficiency of isolation-and-quarantine drops and the imported cases increases. |
format | Online Article Text |
id | pubmed-8763804 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-87638042022-01-19 Cost-Effectiveness of Public Health Measures to Control COVID-19 in China: A Microsimulation Modeling Study Wang, Qiang Shi, Naiyang Huang, Jinxin Yang, Liuqing Cui, Tingting Ai, Jing Ji, Hong Xu, Ke Ahmad, Tauseef Bao, Changjun Jin, Hui Front Public Health Public Health This study aimed to assess the cost-effectiveness of various public health measures in dealing with coronavirus disease 2019 (COVID-19) in China. A stochastic agent-based model was used to simulate the progress of the COVID-19 outbreak in scenario I (imported one case) and scenario II (imported four cases) with a series of public health measures. The main outcomes included the avoided infections and incremental cost-effectiveness ratios (ICERs). Sensitivity analyses were performed to assess uncertainty. The results indicated that isolation-and-quarantine averted the COVID-19 outbreak at the lowest ICERs. The joint strategy of personal protection and isolation-and-quarantine averted one more case than only isolation-and-quarantine with additional costs. The effectiveness of isolation-and-quarantine decreased with lowering quarantine probability and increasing delay time. The strategy that included community containment would be cost-effective when the number of imported cases was >65, or the delay time of the quarantine was more than 5 days, or the quarantine probability was below 25%, based on current assumptions. In conclusion, isolation-and-quarantine was the most cost-effective intervention. However, personal protection combined with isolation-and-quarantine was the optimal strategy for averting more cases. The community containment could be more cost-effective as the efficiency of isolation-and-quarantine drops and the imported cases increases. Frontiers Media S.A. 2022-01-04 /pmc/articles/PMC8763804/ /pubmed/35059369 http://dx.doi.org/10.3389/fpubh.2021.726690 Text en Copyright © 2022 Wang, Shi, Huang, Yang, Cui, Ai, Ji, Xu, Ahmad, Bao and Jin. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Public Health Wang, Qiang Shi, Naiyang Huang, Jinxin Yang, Liuqing Cui, Tingting Ai, Jing Ji, Hong Xu, Ke Ahmad, Tauseef Bao, Changjun Jin, Hui Cost-Effectiveness of Public Health Measures to Control COVID-19 in China: A Microsimulation Modeling Study |
title | Cost-Effectiveness of Public Health Measures to Control COVID-19 in China: A Microsimulation Modeling Study |
title_full | Cost-Effectiveness of Public Health Measures to Control COVID-19 in China: A Microsimulation Modeling Study |
title_fullStr | Cost-Effectiveness of Public Health Measures to Control COVID-19 in China: A Microsimulation Modeling Study |
title_full_unstemmed | Cost-Effectiveness of Public Health Measures to Control COVID-19 in China: A Microsimulation Modeling Study |
title_short | Cost-Effectiveness of Public Health Measures to Control COVID-19 in China: A Microsimulation Modeling Study |
title_sort | cost-effectiveness of public health measures to control covid-19 in china: a microsimulation modeling study |
topic | Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763804/ https://www.ncbi.nlm.nih.gov/pubmed/35059369 http://dx.doi.org/10.3389/fpubh.2021.726690 |
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