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Sonic Hedgehog Pathway Modulation Normalizes Expression of Olig2 in Rostrally Patterned NPCs With Trisomy 21
The intellectual disability found in people with Down syndrome is associated with numerous changes in early brain development, including the proliferation and differentiation of neural progenitor cells (NPCs) and the formation and maintenance of myelin in the brain. To study how early neural precurs...
Autores principales: | Klein, Jenny A., Li, Zhen, Rampam, Sanjeev, Cardini, Jack, Ayoub, Amara, Shaw, Patricia, Rachubinski, Angela L., Espinosa, Joaquin M., Zeldich, Ella, Haydar, Tarik F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763807/ https://www.ncbi.nlm.nih.gov/pubmed/35058753 http://dx.doi.org/10.3389/fncel.2021.794675 |
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