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Targeting of non-coding RNAs encoded by novel MYC enhancers inhibits the proliferation of human hepatic carcinoma cells in vitro

The proto-oncogene MYC is important for development and cell growth, however, its abnormal regulation causes cancer. Recent studies identified distinct enhancers of MYC in various cancers, but any MYC enhancer(s) in hepatocellular carcinoma (HCC) remain(s) elusive. By analyzing H3K27ac enrichment an...

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Detalles Bibliográficos
Autores principales: Choi, Hae In, An, Ga Yeong, Yoo, Eunyoung, Baek, Mina, Chai, Jin Choul, Binas, Bert, Lee, Young Seek, Jung, Kyoung Hwa, Chai, Young Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764030/
https://www.ncbi.nlm.nih.gov/pubmed/35039581
http://dx.doi.org/10.1038/s41598-022-04869-w