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Truncated PARP1 mediates ADP-ribosylation of RNA polymerase III for apoptosis

Caspase-mediated cleavage of PARP1 is a surrogate marker for apoptosis. However, the biological significance of PARP1 cleavage during apoptosis is still unclear. Here, using unbiased protein affinity purification, we show that truncated PARP1 (tPARP1) recognizes the RNA polymerase III (Pol III) comp...

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Detalles Bibliográficos
Autores principales:	Chen, Qian, Ma, Kai, Liu, Xiuhua, Chen, Shih-Hsun, Li, Peng, Yu, Yonghao, Leung, Anthony K. L., Yu, Xiaochun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Singapore 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764063/ https://www.ncbi.nlm.nih.gov/pubmed/35039483 http://dx.doi.org/10.1038/s41421-021-00355-1

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