The three-dimensional structure of Epstein-Barr virus genome varies by latency type and is regulated by PARP1 enzymatic activity

Epstein-Barr virus (EBV) persists in human B-cells by maintaining its chromatinized episomes within the nucleus. We have previously shown that cellular factor Poly [ADP-ribose] polymerase 1 (PARP1) binds the EBV genome, stabilizes CTCF binding at specific loci, and that PARP1 enzymatic activity corr...

Descripción completa

Detalles Bibliográficos
Autores principales: Morgan, Sarah M., Tanizawa, Hideki, Caruso, Lisa Beatrice, Hulse, Michael, Kossenkov, Andrew, Madzo, Jozef, Keith, Kelsey, Tan, Yinfei, Boyle, Sarah, Lieberman, Paul M., Tempera, Italo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764100/
https://www.ncbi.nlm.nih.gov/pubmed/35039491
http://dx.doi.org/10.1038/s41467-021-27894-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764100/
https://www.ncbi.nlm.nih.gov/pubmed/35039491
http://dx.doi.org/10.1038/s41467-021-27894-1

Ejemplares similares