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The three-dimensional structure of Epstein-Barr virus genome varies by latency type and is regulated by PARP1 enzymatic activity
Epstein-Barr virus (EBV) persists in human B-cells by maintaining its chromatinized episomes within the nucleus. We have previously shown that cellular factor Poly [ADP-ribose] polymerase 1 (PARP1) binds the EBV genome, stabilizes CTCF binding at specific loci, and that PARP1 enzymatic activity corr...
Autores principales: | Morgan, Sarah M., Tanizawa, Hideki, Caruso, Lisa Beatrice, Hulse, Michael, Kossenkov, Andrew, Madzo, Jozef, Keith, Kelsey, Tan, Yinfei, Boyle, Sarah, Lieberman, Paul M., Tempera, Italo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764100/ https://www.ncbi.nlm.nih.gov/pubmed/35039491 http://dx.doi.org/10.1038/s41467-021-27894-1 |
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