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Extracting phylogenetic dimensions of coevolution reveals hidden functional signals
Despite the structural and functional information contained in the statistical coupling between pairs of residues in a protein, coevolution associated with function is often obscured by artifactual signals such as genetic drift, which shapes a protein’s phylogenetic history and gives rise to concurr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764114/ https://www.ncbi.nlm.nih.gov/pubmed/35039514 http://dx.doi.org/10.1038/s41598-021-04260-1 |