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Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines

Dementia prevention is a global health priority. In 2019, the World Health Organisation published its first evidence-based guidelines on dementia risk reduction. We are now at the stage where we need effective tools and resources to assess dementia risk and implement these guidelines into policy and...

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Autores principales: Anstey, Kaarin J., Zheng, Lidan, Peters, Ruth, Kootar, Scherazad, Barbera, Mariagnese, Stephen, Ruth, Dua, Tarun, Chowdhary, Neerja, Solomon, Alina, Kivipelto, Miia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764151/
https://www.ncbi.nlm.nih.gov/pubmed/35058873
http://dx.doi.org/10.3389/fneur.2021.765454
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author Anstey, Kaarin J.
Zheng, Lidan
Peters, Ruth
Kootar, Scherazad
Barbera, Mariagnese
Stephen, Ruth
Dua, Tarun
Chowdhary, Neerja
Solomon, Alina
Kivipelto, Miia
author_facet Anstey, Kaarin J.
Zheng, Lidan
Peters, Ruth
Kootar, Scherazad
Barbera, Mariagnese
Stephen, Ruth
Dua, Tarun
Chowdhary, Neerja
Solomon, Alina
Kivipelto, Miia
author_sort Anstey, Kaarin J.
collection PubMed
description Dementia prevention is a global health priority. In 2019, the World Health Organisation published its first evidence-based guidelines on dementia risk reduction. We are now at the stage where we need effective tools and resources to assess dementia risk and implement these guidelines into policy and practice. In this paper we review dementia risk scores as a means to facilitate this process. Specifically, we (a) discuss the rationale for dementia risk assessment, (b) outline some conceptual and methodological issues to consider when reviewing risk scores, (c) evaluate some dementia risk scores that are currently in use, and (d) provide some comments about future directions. A dementia risk score is a weighted composite of risk factors that reflects the likelihood of an individual developing dementia. In general, dementia risks scores have a wide range of implementations and benefits including providing early identification of individuals at high risk, improving risk perception for patients and physicians, and helping health professionals recommend targeted interventions to improve lifestyle habits to decrease dementia risk. A number of risk scores for dementia have been published, and some are widely used in research and clinical trials e.g., CAIDE, ANU-ADRI, and LIBRA. However, there are some methodological concerns and limitations associated with the use of these risk scores and more research is needed to increase their effectiveness and applicability. Overall, we conclude that, while further refinement of risk scores is underway, there is adequate evidence to use these assessments to implement guidelines on dementia risk reduction.
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spelling pubmed-87641512022-01-19 Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines Anstey, Kaarin J. Zheng, Lidan Peters, Ruth Kootar, Scherazad Barbera, Mariagnese Stephen, Ruth Dua, Tarun Chowdhary, Neerja Solomon, Alina Kivipelto, Miia Front Neurol Neurology Dementia prevention is a global health priority. In 2019, the World Health Organisation published its first evidence-based guidelines on dementia risk reduction. We are now at the stage where we need effective tools and resources to assess dementia risk and implement these guidelines into policy and practice. In this paper we review dementia risk scores as a means to facilitate this process. Specifically, we (a) discuss the rationale for dementia risk assessment, (b) outline some conceptual and methodological issues to consider when reviewing risk scores, (c) evaluate some dementia risk scores that are currently in use, and (d) provide some comments about future directions. A dementia risk score is a weighted composite of risk factors that reflects the likelihood of an individual developing dementia. In general, dementia risks scores have a wide range of implementations and benefits including providing early identification of individuals at high risk, improving risk perception for patients and physicians, and helping health professionals recommend targeted interventions to improve lifestyle habits to decrease dementia risk. A number of risk scores for dementia have been published, and some are widely used in research and clinical trials e.g., CAIDE, ANU-ADRI, and LIBRA. However, there are some methodological concerns and limitations associated with the use of these risk scores and more research is needed to increase their effectiveness and applicability. Overall, we conclude that, while further refinement of risk scores is underway, there is adequate evidence to use these assessments to implement guidelines on dementia risk reduction. Frontiers Media S.A. 2022-01-04 /pmc/articles/PMC8764151/ /pubmed/35058873 http://dx.doi.org/10.3389/fneur.2021.765454 Text en Copyright © 2022 Anstey, Zheng, Peters, Kootar, Barbera, Stephen, Dua, Chowdhary, Solomon and Kivipelto. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Anstey, Kaarin J.
Zheng, Lidan
Peters, Ruth
Kootar, Scherazad
Barbera, Mariagnese
Stephen, Ruth
Dua, Tarun
Chowdhary, Neerja
Solomon, Alina
Kivipelto, Miia
Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines
title Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines
title_full Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines
title_fullStr Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines
title_full_unstemmed Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines
title_short Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines
title_sort dementia risk scores and their role in the implementation of risk reduction guidelines
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764151/
https://www.ncbi.nlm.nih.gov/pubmed/35058873
http://dx.doi.org/10.3389/fneur.2021.765454
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