Molecular Mechanism of Puerarin Against Diabetes and its Complications

Puerarin is a predominant component of Radix Puerarin. Despite its anti-tumor and anti-virus effects and efficacy in improving cardiovascular or cerebrovascular diseases and preventing osteoporosis, it has been shown to protect against diabetes and its complications. This review summarizes the curre...

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Detalles Bibliográficos
Autores principales: Bai, Yi-ling, Han, Ling-ling, Qian, Jun-hui, Wang, Hao-zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764238/
https://www.ncbi.nlm.nih.gov/pubmed/35058775
http://dx.doi.org/10.3389/fphar.2021.780419
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author Bai, Yi-ling
Han, Ling-ling
Qian, Jun-hui
Wang, Hao-zhong
author_facet Bai, Yi-ling
Han, Ling-ling
Qian, Jun-hui
Wang, Hao-zhong
author_sort Bai, Yi-ling
collection PubMed
description Puerarin is a predominant component of Radix Puerarin. Despite its anti-tumor and anti-virus effects and efficacy in improving cardiovascular or cerebrovascular diseases and preventing osteoporosis, it has been shown to protect against diabetes and its complications. This review summarizes the current knowledge on Puerarin in diabetes and related complications, aiming to provide an overview of antidiabetic mechanisms of Puerarin and new targets for treatment.
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spelling pubmed-87642382022-01-19 Molecular Mechanism of Puerarin Against Diabetes and its Complications Bai, Yi-ling Han, Ling-ling Qian, Jun-hui Wang, Hao-zhong Front Pharmacol Pharmacology Puerarin is a predominant component of Radix Puerarin. Despite its anti-tumor and anti-virus effects and efficacy in improving cardiovascular or cerebrovascular diseases and preventing osteoporosis, it has been shown to protect against diabetes and its complications. This review summarizes the current knowledge on Puerarin in diabetes and related complications, aiming to provide an overview of antidiabetic mechanisms of Puerarin and new targets for treatment. Frontiers Media S.A. 2022-01-04 /pmc/articles/PMC8764238/ /pubmed/35058775 http://dx.doi.org/10.3389/fphar.2021.780419 Text en Copyright © 2022 Bai, Han, Qian and Wang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Bai, Yi-ling
Han, Ling-ling
Qian, Jun-hui
Wang, Hao-zhong
Molecular Mechanism of Puerarin Against Diabetes and its Complications
title Molecular Mechanism of Puerarin Against Diabetes and its Complications
title_full Molecular Mechanism of Puerarin Against Diabetes and its Complications
title_fullStr Molecular Mechanism of Puerarin Against Diabetes and its Complications
title_full_unstemmed Molecular Mechanism of Puerarin Against Diabetes and its Complications
title_short Molecular Mechanism of Puerarin Against Diabetes and its Complications
title_sort molecular mechanism of puerarin against diabetes and its complications
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764238/
https://www.ncbi.nlm.nih.gov/pubmed/35058775
http://dx.doi.org/10.3389/fphar.2021.780419
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