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Long-Term Enhancement of NMDA Receptor Function in Inhibitory Neurons Preferentially Modulates Potassium Channels and Cell Adhesion Molecules

Effectively enhancing the activity of inhibitory neurons has great therapeutic potentials since their reduced function/activity has significant contributions to pathology in various brain diseases. We showed previously that NMDAR positive allosteric modulator GNE-8324 and M-8324 selectively increase...

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Detalles Bibliográficos
Autores principales: Xia, Dan, Zhang, Xinyang, Deng, Di, Ma, Xiaoyan, Masri, Samer, Wang, Jianzheng, Bao, Shaowen, Hu, Songnian, Zhou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764260/
https://www.ncbi.nlm.nih.gov/pubmed/35058780
http://dx.doi.org/10.3389/fphar.2021.796179