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Long-Term Enhancement of NMDA Receptor Function in Inhibitory Neurons Preferentially Modulates Potassium Channels and Cell Adhesion Molecules
Effectively enhancing the activity of inhibitory neurons has great therapeutic potentials since their reduced function/activity has significant contributions to pathology in various brain diseases. We showed previously that NMDAR positive allosteric modulator GNE-8324 and M-8324 selectively increase...
Autores principales: | Xia, Dan, Zhang, Xinyang, Deng, Di, Ma, Xiaoyan, Masri, Samer, Wang, Jianzheng, Bao, Shaowen, Hu, Songnian, Zhou, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764260/ https://www.ncbi.nlm.nih.gov/pubmed/35058780 http://dx.doi.org/10.3389/fphar.2021.796179 |
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