Cargando…

Perilla Leaf Extract (PLE) Attenuates COPD Airway Inflammation via the TLR4/Syk/PKC/NF-κB Pathway In Vivo and In Vitro

Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disease characterized by persistent airflow limitation but still lacking effective treatments. Perilla frutescens (L.) Britt., an important traditional medicinal plant with excellent antioxidant and anti-inflammatory propert...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuan, Jiqiao, Li, Xuyu, Fang, Nan, Li, Ping, Zhang, Ziqian, Lin, Mingbao, Hou, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764369/ https://www.ncbi.nlm.nih.gov/pubmed/35058774 http://dx.doi.org/10.3389/fphar.2021.763624

Ejemplares similares

Multiple Components Rapidly Screened from Perilla Leaves Attenuate Asthma Airway Inflammation by Synergistic Targeting on Syk
por: Yang, Hui, et al.
Publicado: (2020)

Syk-Targeted, a New 3-Arylbenzofuran Derivative EAPP-2 Blocks Airway Inflammation of Asthma–COPD Overlap in vivo and in vitro
por: Li, Shuyi, et al.
Publicado: (2021)

Chondroprotective and anti‐inflammatory effects of amurensin H by regulating TLR4/Syk/NF‐κB signals
por: Ma, Pei, et al.
Publicado: (2019)

Amurensin H, a Derivative From Resveratrol, Ameliorates Lipopolysaccharide/Cigarette Smoke–Induced Airway Inflammation by Blocking the Syk/NF-κB Pathway
por: Fan, Yannan, et al.
Publicado: (2019)

Perilla Leaf Extract Attenuates Asthma Airway Inflammation by Blocking the Syk Pathway
por: Yang, Hui, et al.
Publicado: (2021)

Comparative RNA-Seq Transcriptome Analysis on Pulmonary Inflammation in a Mouse Model of Asthma–COPD Overlap Syndrome
por: Ma, Pei, et al.
Publicado: (2021)

Tulobuterol patch alleviates allergic asthmic inflammation by blockade of Syk and NF-κB activation in mice
por: Fu, Lixia, et al.
Publicado: (2018)

PMA inhibits endothelial cell migration through activating the PKC-δ/Syk/NF-κB-mediated up-regulation of Thy-1
por: Wen, Heng-Ching, et al.
Publicado: (2018)

The effect of Perilla (Perilla frutescens) leaf extracts on the quality of surimi fish balls
por: Zhao, Yueliang, et al.
Publicado: (2019)

Pig liver esterases PLE1 and PLE6: heterologous expression, hydrolysis of common antibiotics and pharmacological consequences
por: Zhou, Qiongqiong, et al.
Publicado: (2019)

PKC-Dependent Human Monocyte Adhesion Requires AMPK and Syk Activation
por: Chang, Mei-Ying, et al.
Publicado: (2012)

Molecular and Biochemical Differences of the Tandem and Cold-Adapted PET Hydrolases Ple628 and Ple629, Isolated From a Marine Microbial Consortium
por: Meyer Cifuentes, Ingrid E., et al.
Publicado: (2022)

Perilla (Perilla frutescens) leaf extract inhibits SARS-CoV-2 via direct virus inactivation
por: Tang, Wen-Fang, et al.
Publicado: (2021)

Actomyosin fibers DApPLE epithelial apical junctions
por: Manzano, Alejandra R., et al.
Publicado: (2022)

Dissipation, persistence, and risk assessment of fluxapyroxad and penthiopyrad residues in perilla leaf (Perilla frutescens var. japonica Hara)
por: Noh, Hyun H., et al.
Publicado: (2019)

The FcγRIII Engagement Augments PMA-Stimulated Neutrophil Extracellular Traps (NETs) Formation by Granulocytes Partially via Cross-Talk between Syk-ERK-NF-κB and PKC-ROS Signaling Pathways
por: Lu, Cheng-Hsun, et al.
Publicado: (2021)

Genetic signature of human longevity in PKC and NF‐κB signaling
por: Ryu, Seungjin, et al.
Publicado: (2021)

Dexmedetomidine alleviates airway hyperresponsiveness and allergic airway inflammation through the TLR4/NF-κB signaling pathway in mice
por: Xiao, Shilin, et al.
Publicado: (2022)

Anti-Inflammatory Effect of Meriania hexamera Sprague by Targeting Syk Kinase in NF-κB Signaling
por: Kwon, Ki Woong, et al.
Publicado: (2023)

PKC-δ isoform plays a crucial role in Tat-TLR4 signalling pathway to activate NF-κB and CXCL8 production
por: Serrero, Manutea, et al.
Publicado: (2017)

Role and mechanism of the Dectin-1-mediated Syk/NF-κB signaling pathway in Talaromyces marneffei infection
por: Peng, Yang, et al.
Publicado: (2022)

Orally delivered perilla (Perilla frutescens) leaf extract effectively inhibits SARS-CoV-2 infection in a Syrian hamster model
por: Chin, Yuan-Fan, et al.
Publicado: (2022)

ExamPle: explainable deep learning framework for the prediction of plant small secreted peptides
por: Li, Zhongshen, et al.
Publicado: (2023)

NaPLeS: a natural products likeness scorer—web application and database
por: Sorokina, Maria, et al.
Publicado: (2019)

Comparison of Growth Kinetics of Various Pathogenic E. coli on Fresh Perilla Leaf
por: Kim, Juhui, et al.
Publicado: (2013)

Perilla frutescens Leaf Alters the Rumen Microbial Community of Lactating Dairy Cows
por: Sun, Zhiqiang, et al.
Publicado: (2019)

Temperature-induced embryonic diapause in chickens is mediated by PKC-NF-κB-IRF1 signaling
por: Ren, Junxiao, et al.
Publicado: (2023)

Syk and Hrs Regulate TLR3-Mediated Antiviral Response in Murine Astrocytes
por: Mielcarska, Matylda B., et al.
Publicado: (2019)

Ranunculus bulumei Methanol Extract Exerts Anti-Inflammatory Activity by Targeting Src/Syk in NF-κB Signaling
por: Hong, Yo Han, et al.
Publicado: (2020)

Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets
por: Zhang, Pengyu, et al.
Publicado: (2023)

TEMPI: probabilistic modeling time-evolving differential PPI networks with multiPle information
por: Kim, Yongsoo, et al.
Publicado: (2014)

Regulation of the activity of the bacterial histidine kinase PleC by the scaffolding protein PodJ
por: Zhang, Chao, et al.
Publicado: (2022)

Comparative transcriptome sequencing analysis to postulate the scheme of regulated leaf coloration in Perilla frutescens
por: Liu, Xiaoning, et al.
Publicado: (2023)

NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis
por: Maeda, Shin
Publicado: (2010)

LOMIX, a Mixture of Flaxseed Linusorbs, Exerts Anti-Inflammatory Effects through Src and Syk in the NF-κB Pathway
por: Ratan, Zubair Ahmed, et al.
Publicado: (2020)

Loss of NF1 in Melanoma Confers Sensitivity to SYK Kinase Inhibition
por: Abecunas, Cara, et al.
Publicado: (2023)

Triterpene Acids of Loquat Leaf Improve Inflammation in Cigarette Smoking Induced COPD by Regulating AMPK/Nrf2 and NFκB Pathways
por: Jian, Tunyu, et al.
Publicado: (2020)

Polyoxygenated Cholesterol Ester Hydroperoxide Activates TLR4 and SYK Dependent Signaling in Macrophages
por: Choi, Soo-Ho, et al.
Publicado: (2013)

Dexmedetomidine Protects against Airway Inflammation and Airway Remodeling in a Murine Model of Chronic Asthma through TLR4/NF-κB Signaling Pathway
por: Zhou, Ying, et al.
Publicado: (2023)

Importance of extra- and intracellular domains of TLR1 and TLR2 in NFκB signaling
por: Sandor, Frantisek, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_0o4v1dh3ekao2fah25b9t2d10r