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CD33 Delineates Two Functionally Distinct NK Cell Populations Divergent in Cytokine Production and Antibody-Mediated Cellular Cytotoxicity
The generation and expansion of functionally competent NK cells in vitro is of great interest for their application in immunotherapy of cancer. Since CD33 constitutes a promising target for immunotherapy of myeloid malignancies, NK cells expressing a CD33-specific chimeric antigen receptor (CAR) wer...
Autores principales: | Hejazi, Maryam, Zhang, Congcong, Bennstein, Sabrina B., Balz, Vera, Reusing, Sarah B., Quadflieg, Melissa, Hoerster, Keven, Heinrichs, Stefan, Hanenberg, Helmut, Oberbeck, Sebastian, Nitsche, Marcus, Cramer, Sophie, Pfeifer, Rita, Oberoi, Pranav, Rühl, Heiko, Oldenburg, Johannes, Brossart, Peter, Horn, Peter A., Babor, Florian, Wels, Winfried S., Fischer, Johannes C., Möker, Nina, Uhrberg, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764454/ https://www.ncbi.nlm.nih.gov/pubmed/35058934 http://dx.doi.org/10.3389/fimmu.2021.798087 |
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