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Evaluation of early complications, outcome, and mortality in Coronavirus Disease 2019 (COVID-19) infection in patients who underwent orthopedic surgery

BACKGROUND: A higher mortality and morbidity rate has been reported in COVID-19 patients undergoing surgery. To reduce the morbidity and mortality rate in COVID-19 patients undergoing orthopedic procedures, we aimed to increase the threshold for surgical planning. METHODS: In a prospective cohort st...

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Autores principales: Mohammadpour, Mehdi, Yazdi, Hamidreza, Bagherifard, Abolfazl, Jabalameli, Mahmoud, Moghtadaei, Mehdi, Torkaman, Ali, Yahyazadeh, Hooman, Ghaderi, Mohammad Taher, Fanaeian, Mohammad Mahdi, Langeroudi, Moein Khaleghi, Hashemi, Peyman, Razi, Saeed, Karimpour, Amer, Lirgeshasi, Sam Bemani, Bahari, Milad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764495/
https://www.ncbi.nlm.nih.gov/pubmed/35042507
http://dx.doi.org/10.1186/s12891-022-05010-8
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author Mohammadpour, Mehdi
Yazdi, Hamidreza
Bagherifard, Abolfazl
Jabalameli, Mahmoud
Moghtadaei, Mehdi
Torkaman, Ali
Yahyazadeh, Hooman
Ghaderi, Mohammad Taher
Fanaeian, Mohammad Mahdi
Langeroudi, Moein Khaleghi
Hashemi, Peyman
Razi, Saeed
Karimpour, Amer
Lirgeshasi, Sam Bemani
Bahari, Milad
author_facet Mohammadpour, Mehdi
Yazdi, Hamidreza
Bagherifard, Abolfazl
Jabalameli, Mahmoud
Moghtadaei, Mehdi
Torkaman, Ali
Yahyazadeh, Hooman
Ghaderi, Mohammad Taher
Fanaeian, Mohammad Mahdi
Langeroudi, Moein Khaleghi
Hashemi, Peyman
Razi, Saeed
Karimpour, Amer
Lirgeshasi, Sam Bemani
Bahari, Milad
author_sort Mohammadpour, Mehdi
collection PubMed
description BACKGROUND: A higher mortality and morbidity rate has been reported in COVID-19 patients undergoing surgery. To reduce the morbidity and mortality rate in COVID-19 patients undergoing orthopedic procedures, we aimed to increase the threshold for surgical planning. METHODS: In a prospective cohort study, COVID-19 patients who underwent elective or emergent orthopedic surgery in three orthopedic surgery centers from February 2020 to September 2020 were included. In this period, 6751 patients were scheduled for orthopedic surgery. To increase surgical threshold planning, all patients with grade 5 of the American Society of Anesthesiologists (ASA) classification and patients with COVID-19 related moderate to severe pulmonary involvement were identified as high-risk patients and were excluded. RESULTS: 35 deaths occurred during the study. The frequency of deaths was significantly higher in patients with COVID-19, 6 (9.4%) than patients without COVID-19, 29 (0. 43%). The average hospitalization stay was 12.8 ± 12.1 days. The odds ratio (OR) for death was significantly higher in patients with COVID-19 than patients without COVID-19. [OR: 8.13, Confidence interval 95% (CI95%) (5.02–11.25), P: 0.001]. Four (6.3%) COVID-19-associated complications were recorded in this series that all were respiratory failure requiring unexpected postoperative ventilation. Twenty surgical complications (31.3%) were recorded. The odds ratio for ICU admission was significantly higher in patients with COVID-19 than patients without COVID-19. [OR: 5.46, CI 95% (2.68–8.68), P: 0.001]. CONCLUSIONS: An increased threshold for orthopedic surgery is suggested for COVID-19 patients with a mortality rate of 9.3%, which is less than the mortality rate in other studies. Level of evidence III. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12891-022-05010-8.
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spelling pubmed-87644952022-01-18 Evaluation of early complications, outcome, and mortality in Coronavirus Disease 2019 (COVID-19) infection in patients who underwent orthopedic surgery Mohammadpour, Mehdi Yazdi, Hamidreza Bagherifard, Abolfazl Jabalameli, Mahmoud Moghtadaei, Mehdi Torkaman, Ali Yahyazadeh, Hooman Ghaderi, Mohammad Taher Fanaeian, Mohammad Mahdi Langeroudi, Moein Khaleghi Hashemi, Peyman Razi, Saeed Karimpour, Amer Lirgeshasi, Sam Bemani Bahari, Milad BMC Musculoskelet Disord Research BACKGROUND: A higher mortality and morbidity rate has been reported in COVID-19 patients undergoing surgery. To reduce the morbidity and mortality rate in COVID-19 patients undergoing orthopedic procedures, we aimed to increase the threshold for surgical planning. METHODS: In a prospective cohort study, COVID-19 patients who underwent elective or emergent orthopedic surgery in three orthopedic surgery centers from February 2020 to September 2020 were included. In this period, 6751 patients were scheduled for orthopedic surgery. To increase surgical threshold planning, all patients with grade 5 of the American Society of Anesthesiologists (ASA) classification and patients with COVID-19 related moderate to severe pulmonary involvement were identified as high-risk patients and were excluded. RESULTS: 35 deaths occurred during the study. The frequency of deaths was significantly higher in patients with COVID-19, 6 (9.4%) than patients without COVID-19, 29 (0. 43%). The average hospitalization stay was 12.8 ± 12.1 days. The odds ratio (OR) for death was significantly higher in patients with COVID-19 than patients without COVID-19. [OR: 8.13, Confidence interval 95% (CI95%) (5.02–11.25), P: 0.001]. Four (6.3%) COVID-19-associated complications were recorded in this series that all were respiratory failure requiring unexpected postoperative ventilation. Twenty surgical complications (31.3%) were recorded. The odds ratio for ICU admission was significantly higher in patients with COVID-19 than patients without COVID-19. [OR: 5.46, CI 95% (2.68–8.68), P: 0.001]. CONCLUSIONS: An increased threshold for orthopedic surgery is suggested for COVID-19 patients with a mortality rate of 9.3%, which is less than the mortality rate in other studies. Level of evidence III. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12891-022-05010-8. BioMed Central 2022-01-18 /pmc/articles/PMC8764495/ /pubmed/35042507 http://dx.doi.org/10.1186/s12891-022-05010-8 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Mohammadpour, Mehdi
Yazdi, Hamidreza
Bagherifard, Abolfazl
Jabalameli, Mahmoud
Moghtadaei, Mehdi
Torkaman, Ali
Yahyazadeh, Hooman
Ghaderi, Mohammad Taher
Fanaeian, Mohammad Mahdi
Langeroudi, Moein Khaleghi
Hashemi, Peyman
Razi, Saeed
Karimpour, Amer
Lirgeshasi, Sam Bemani
Bahari, Milad
Evaluation of early complications, outcome, and mortality in Coronavirus Disease 2019 (COVID-19) infection in patients who underwent orthopedic surgery
title Evaluation of early complications, outcome, and mortality in Coronavirus Disease 2019 (COVID-19) infection in patients who underwent orthopedic surgery
title_full Evaluation of early complications, outcome, and mortality in Coronavirus Disease 2019 (COVID-19) infection in patients who underwent orthopedic surgery
title_fullStr Evaluation of early complications, outcome, and mortality in Coronavirus Disease 2019 (COVID-19) infection in patients who underwent orthopedic surgery
title_full_unstemmed Evaluation of early complications, outcome, and mortality in Coronavirus Disease 2019 (COVID-19) infection in patients who underwent orthopedic surgery
title_short Evaluation of early complications, outcome, and mortality in Coronavirus Disease 2019 (COVID-19) infection in patients who underwent orthopedic surgery
title_sort evaluation of early complications, outcome, and mortality in coronavirus disease 2019 (covid-19) infection in patients who underwent orthopedic surgery
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764495/
https://www.ncbi.nlm.nih.gov/pubmed/35042507
http://dx.doi.org/10.1186/s12891-022-05010-8
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