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A Toxin-Conjugated Recombinant Protein Targeting gp120 and gp41 for Inactivating HIV-1 Virions and Killing Latency-Reversing Agent-Reactivated Latent Cells

Application of the combination antiretroviral therapy (cART) has reduced AIDS to a manageable chronic infectious disease. However, HIV/AIDS cannot be cured because of the presence of latent reservoirs, thus calling for the development of antiretroviral drugs that can eliminate latency-reversing agen...

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Detalles Bibliográficos
Autores principales: Wang, Xinling, Xu, Wei, Liu, Zezhong, Wu, Yanling, Wang, Qian, Cao, Miao, Ying, Tianlei, He, Na, Lu, Lu, Jiang, Shibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764533/
https://www.ncbi.nlm.nih.gov/pubmed/35038908
http://dx.doi.org/10.1128/mbio.03384-21