Cargando…

Novel Function of Avian p53 in Binding to ALV-J LTR Contributes to Its Antiviral Roles

Accumulating evidence suggests that p53 is involved in viral infection. However, it remains elusive whether avian p53 orchestrates avian leukosis virus (ALV) replication. We showed that p53 recruits the histone deacetylase 1 and 2 (HDAC1/2) complex to the ALV promoter to shut off ALV's promoter...

Descripción completa

Detalles Bibliográficos
Autores principales: Duan, Yueyue, Cao, Liyan, Yuan, Cong, Suo, Xuepeng, Kong, Xiangyu, Gao, Yulong, Li, Xiangtong, Zheng, Haixue, Wang, Xiaomei, Wang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764537/
https://www.ncbi.nlm.nih.gov/pubmed/35038897
http://dx.doi.org/10.1128/mbio.03287-21