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Integrative Reverse Genetic Analysis Identifies Polymorphisms Contributing to Decreased Antimicrobial Agent Susceptibility in Streptococcus pyogenes

Identification of genetic polymorphisms causing increased antibiotic resistance in bacterial pathogens traditionally has proceeded from observed phenotype to defined mutant genotype. The availability of large collections of microbial genome sequences that lack antibiotic susceptibility metadata prov...

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Detalles Bibliográficos
Autores principales:	Beres, Stephen B., Zhu, Luchang, Pruitt, Layne, Olsen, Randall J., Faili, Ahmad, Kayal, Samer, Musser, James M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764543/ https://www.ncbi.nlm.nih.gov/pubmed/35038921 http://dx.doi.org/10.1128/mbio.03618-21

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