A case of Pneumocystis jirovecii pneumonia in a patient with acquired immune deficiency syndrome who showed eosinophilia and an increased serum TARC/CCL17 level

Pneumocystis jirovecii pneumonia (PCP) in patients with acquired immune deficiency syndrome (AIDS) shows eosinophilic pneumonia like condition. The detailed mechanisms how AIDS-associated PCP causes eosinophilic pneumonia has not been elucidated, but it has been suggested that beta-D-glucan, a major...

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Autores principales: Yabuuchi, Yuki, Matsuyama, Masashi, Matsumura, Sosuke, Nakajima, Masayuki, Kiyasu, Yoshihiko, Takeuchi, Yuto, Murata, Yoshihiko, Matsuoka, Ryota, Noguchi, Masayuki, Hizawa, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764545/
https://www.ncbi.nlm.nih.gov/pubmed/35127079
http://dx.doi.org/10.4081/mrm.2022.802
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author Yabuuchi, Yuki
Matsuyama, Masashi
Matsumura, Sosuke
Nakajima, Masayuki
Kiyasu, Yoshihiko
Takeuchi, Yuto
Murata, Yoshihiko
Matsuoka, Ryota
Noguchi, Masayuki
Hizawa, Nobuyuki
author_facet Yabuuchi, Yuki
Matsuyama, Masashi
Matsumura, Sosuke
Nakajima, Masayuki
Kiyasu, Yoshihiko
Takeuchi, Yuto
Murata, Yoshihiko
Matsuoka, Ryota
Noguchi, Masayuki
Hizawa, Nobuyuki
author_sort Yabuuchi, Yuki
collection PubMed
description Pneumocystis jirovecii pneumonia (PCP) in patients with acquired immune deficiency syndrome (AIDS) shows eosinophilic pneumonia like condition. The detailed mechanisms how AIDS-associated PCP causes eosinophilic pneumonia has not been elucidated, but it has been suggested that beta-D-glucan, a major component of Pneumocystis jirovecii, and T helper type 2 immunity may be involved in the mechanism of eosinophilia in the lung. We experienced the case who developed an eosinophilic pneumonia-like condition in a patient with AIDS-associated PCP, whose clinical course indicated the importance of TARC/CCL17 but not IL-4 and IL-5 as involved in eosinophilia caused by HIV and Pneumocystis jirovecii infection.
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spelling pubmed-87645452022-02-03 A case of Pneumocystis jirovecii pneumonia in a patient with acquired immune deficiency syndrome who showed eosinophilia and an increased serum TARC/CCL17 level Yabuuchi, Yuki Matsuyama, Masashi Matsumura, Sosuke Nakajima, Masayuki Kiyasu, Yoshihiko Takeuchi, Yuto Murata, Yoshihiko Matsuoka, Ryota Noguchi, Masayuki Hizawa, Nobuyuki Multidiscip Respir Med Case Report Pneumocystis jirovecii pneumonia (PCP) in patients with acquired immune deficiency syndrome (AIDS) shows eosinophilic pneumonia like condition. The detailed mechanisms how AIDS-associated PCP causes eosinophilic pneumonia has not been elucidated, but it has been suggested that beta-D-glucan, a major component of Pneumocystis jirovecii, and T helper type 2 immunity may be involved in the mechanism of eosinophilia in the lung. We experienced the case who developed an eosinophilic pneumonia-like condition in a patient with AIDS-associated PCP, whose clinical course indicated the importance of TARC/CCL17 but not IL-4 and IL-5 as involved in eosinophilia caused by HIV and Pneumocystis jirovecii infection. PAGEPress Publications, Pavia, Italy 2022-01-12 /pmc/articles/PMC8764545/ /pubmed/35127079 http://dx.doi.org/10.4081/mrm.2022.802 Text en ©Copyright: the Author(s) https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Yabuuchi, Yuki
Matsuyama, Masashi
Matsumura, Sosuke
Nakajima, Masayuki
Kiyasu, Yoshihiko
Takeuchi, Yuto
Murata, Yoshihiko
Matsuoka, Ryota
Noguchi, Masayuki
Hizawa, Nobuyuki
A case of Pneumocystis jirovecii pneumonia in a patient with acquired immune deficiency syndrome who showed eosinophilia and an increased serum TARC/CCL17 level
title A case of Pneumocystis jirovecii pneumonia in a patient with acquired immune deficiency syndrome who showed eosinophilia and an increased serum TARC/CCL17 level
title_full A case of Pneumocystis jirovecii pneumonia in a patient with acquired immune deficiency syndrome who showed eosinophilia and an increased serum TARC/CCL17 level
title_fullStr A case of Pneumocystis jirovecii pneumonia in a patient with acquired immune deficiency syndrome who showed eosinophilia and an increased serum TARC/CCL17 level
title_full_unstemmed A case of Pneumocystis jirovecii pneumonia in a patient with acquired immune deficiency syndrome who showed eosinophilia and an increased serum TARC/CCL17 level
title_short A case of Pneumocystis jirovecii pneumonia in a patient with acquired immune deficiency syndrome who showed eosinophilia and an increased serum TARC/CCL17 level
title_sort case of pneumocystis jirovecii pneumonia in a patient with acquired immune deficiency syndrome who showed eosinophilia and an increased serum tarc/ccl17 level
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764545/
https://www.ncbi.nlm.nih.gov/pubmed/35127079
http://dx.doi.org/10.4081/mrm.2022.802
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