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A Deep Residual U-Net Algorithm for Automatic Detection and Quantification of Ascites on Abdominopelvic Computed Tomography Images Acquired in the Emergency Department: Model Development and Validation

BACKGROUND: Detection and quantification of intra-abdominal free fluid (ie, ascites) on computed tomography (CT) images are essential processes for finding emergent or urgent conditions in patients. In an emergency department, automatic detection and quantification of ascites will be beneficial. OBJ...

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Autores principales: Ko, Hoon, Huh, Jimi, Kim, Kyung Won, Chung, Heewon, Ko, Yousun, Kim, Jai Keun, Lee, Jei Hee, Lee, Jinseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764611/
https://www.ncbi.nlm.nih.gov/pubmed/34982041
http://dx.doi.org/10.2196/34415
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author Ko, Hoon
Huh, Jimi
Kim, Kyung Won
Chung, Heewon
Ko, Yousun
Kim, Jai Keun
Lee, Jei Hee
Lee, Jinseok
author_facet Ko, Hoon
Huh, Jimi
Kim, Kyung Won
Chung, Heewon
Ko, Yousun
Kim, Jai Keun
Lee, Jei Hee
Lee, Jinseok
author_sort Ko, Hoon
collection PubMed
description BACKGROUND: Detection and quantification of intra-abdominal free fluid (ie, ascites) on computed tomography (CT) images are essential processes for finding emergent or urgent conditions in patients. In an emergency department, automatic detection and quantification of ascites will be beneficial. OBJECTIVE: We aimed to develop an artificial intelligence (AI) algorithm for the automatic detection and quantification of ascites simultaneously using a single deep learning model (DLM). METHODS: We developed 2D DLMs based on deep residual U-Net, U-Net, bidirectional U-Net, and recurrent residual U-Net (R2U-Net) algorithms to segment areas of ascites on abdominopelvic CT images. Based on segmentation results, the DLMs detected ascites by classifying CT images into ascites images and nonascites images. The AI algorithms were trained using 6337 CT images from 160 subjects (80 with ascites and 80 without ascites) and tested using 1635 CT images from 40 subjects (20 with ascites and 20 without ascites). The performance of the AI algorithms was evaluated for diagnostic accuracy of ascites detection and for segmentation accuracy of ascites areas. Of these DLMs, we proposed an AI algorithm with the best performance. RESULTS: The segmentation accuracy was the highest for the deep residual U-Net model with a mean intersection over union (mIoU) value of 0.87, followed by U-Net, bidirectional U-Net, and R2U-Net models (mIoU values of 0.80, 0.77, and 0.67, respectively). The detection accuracy was the highest for the deep residual U-Net model (0.96), followed by U-Net, bidirectional U-Net, and R2U-Net models (0.90, 0.88, and 0.82, respectively). The deep residual U-Net model also achieved high sensitivity (0.96) and high specificity (0.96). CONCLUSIONS: We propose a deep residual U-Net–based AI algorithm for automatic detection and quantification of ascites on abdominopelvic CT scans, which provides excellent performance.
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spelling pubmed-87646112022-02-03 A Deep Residual U-Net Algorithm for Automatic Detection and Quantification of Ascites on Abdominopelvic Computed Tomography Images Acquired in the Emergency Department: Model Development and Validation Ko, Hoon Huh, Jimi Kim, Kyung Won Chung, Heewon Ko, Yousun Kim, Jai Keun Lee, Jei Hee Lee, Jinseok J Med Internet Res Original Paper BACKGROUND: Detection and quantification of intra-abdominal free fluid (ie, ascites) on computed tomography (CT) images are essential processes for finding emergent or urgent conditions in patients. In an emergency department, automatic detection and quantification of ascites will be beneficial. OBJECTIVE: We aimed to develop an artificial intelligence (AI) algorithm for the automatic detection and quantification of ascites simultaneously using a single deep learning model (DLM). METHODS: We developed 2D DLMs based on deep residual U-Net, U-Net, bidirectional U-Net, and recurrent residual U-Net (R2U-Net) algorithms to segment areas of ascites on abdominopelvic CT images. Based on segmentation results, the DLMs detected ascites by classifying CT images into ascites images and nonascites images. The AI algorithms were trained using 6337 CT images from 160 subjects (80 with ascites and 80 without ascites) and tested using 1635 CT images from 40 subjects (20 with ascites and 20 without ascites). The performance of the AI algorithms was evaluated for diagnostic accuracy of ascites detection and for segmentation accuracy of ascites areas. Of these DLMs, we proposed an AI algorithm with the best performance. RESULTS: The segmentation accuracy was the highest for the deep residual U-Net model with a mean intersection over union (mIoU) value of 0.87, followed by U-Net, bidirectional U-Net, and R2U-Net models (mIoU values of 0.80, 0.77, and 0.67, respectively). The detection accuracy was the highest for the deep residual U-Net model (0.96), followed by U-Net, bidirectional U-Net, and R2U-Net models (0.90, 0.88, and 0.82, respectively). The deep residual U-Net model also achieved high sensitivity (0.96) and high specificity (0.96). CONCLUSIONS: We propose a deep residual U-Net–based AI algorithm for automatic detection and quantification of ascites on abdominopelvic CT scans, which provides excellent performance. JMIR Publications 2022-01-03 /pmc/articles/PMC8764611/ /pubmed/34982041 http://dx.doi.org/10.2196/34415 Text en ©Hoon Ko, Jimi Huh, Kyung Won Kim, Heewon Chung, Yousun Ko, Jai Keun Kim, Jei Hee Lee, Jinseok Lee. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 03.01.2022. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.
spellingShingle Original Paper
Ko, Hoon
Huh, Jimi
Kim, Kyung Won
Chung, Heewon
Ko, Yousun
Kim, Jai Keun
Lee, Jei Hee
Lee, Jinseok
A Deep Residual U-Net Algorithm for Automatic Detection and Quantification of Ascites on Abdominopelvic Computed Tomography Images Acquired in the Emergency Department: Model Development and Validation
title A Deep Residual U-Net Algorithm for Automatic Detection and Quantification of Ascites on Abdominopelvic Computed Tomography Images Acquired in the Emergency Department: Model Development and Validation
title_full A Deep Residual U-Net Algorithm for Automatic Detection and Quantification of Ascites on Abdominopelvic Computed Tomography Images Acquired in the Emergency Department: Model Development and Validation
title_fullStr A Deep Residual U-Net Algorithm for Automatic Detection and Quantification of Ascites on Abdominopelvic Computed Tomography Images Acquired in the Emergency Department: Model Development and Validation
title_full_unstemmed A Deep Residual U-Net Algorithm for Automatic Detection and Quantification of Ascites on Abdominopelvic Computed Tomography Images Acquired in the Emergency Department: Model Development and Validation
title_short A Deep Residual U-Net Algorithm for Automatic Detection and Quantification of Ascites on Abdominopelvic Computed Tomography Images Acquired in the Emergency Department: Model Development and Validation
title_sort deep residual u-net algorithm for automatic detection and quantification of ascites on abdominopelvic computed tomography images acquired in the emergency department: model development and validation
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764611/
https://www.ncbi.nlm.nih.gov/pubmed/34982041
http://dx.doi.org/10.2196/34415
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