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FASN-dependent de novo lipogenesis is required for brain development
Fate and behavior of neural progenitor cells are tightly regulated during mammalian brain development. Metabolic pathways, such as glycolysis and oxidative phosphorylation, that are required for supplying energy and providing molecular building blocks to generate cells govern progenitor function. Ho...
Autores principales: | Gonzalez-Bohorquez, Daniel, Gallego López, Isabel M., Jaeger, Baptiste N., Pfammatter, Sibylle, Bowers, Megan, Semenkovich, Clay F., Jessberger, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764667/ https://www.ncbi.nlm.nih.gov/pubmed/34996870 http://dx.doi.org/10.1073/pnas.2112040119 |
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