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MUC5B regulates goblet cell differentiation and reduces inflammation in a murine COPD model
BACKGROUND: Airway mucus hypersecretion is one of the important pathological features of chronic obstructive pulmonary disease (COPD). MUC5B is the main mucin expressed in the airways of COPD patients and has been indicated to play an important role in airway defense. However, the specific biologica...
Autores principales: | Huang, Xuan, Guan, Weijie, Xiang, Bin, Wang, Wei, Xie, Yanqing, Zheng, Jinping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764756/ https://www.ncbi.nlm.nih.gov/pubmed/35042537 http://dx.doi.org/10.1186/s12931-021-01920-8 |
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