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MUC5B regulates goblet cell differentiation and reduces inflammation in a murine COPD model

BACKGROUND: Airway mucus hypersecretion is one of the important pathological features of chronic obstructive pulmonary disease (COPD). MUC5B is the main mucin expressed in the airways of COPD patients and has been indicated to play an important role in airway defense. However, the specific biologica...

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Detalles Bibliográficos
Autores principales: Huang, Xuan, Guan, Weijie, Xiang, Bin, Wang, Wei, Xie, Yanqing, Zheng, Jinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764756/
https://www.ncbi.nlm.nih.gov/pubmed/35042537
http://dx.doi.org/10.1186/s12931-021-01920-8

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