4,5-Dimethoxycanthin-6-one is a novel LSD1 inhibitor that inhibits proliferation of glioblastoma cells and induces apoptosis and pyroptosis

BACKGROUND: Glioblastoma is one of the most common fatal intracranial malignancies. Lysine-specific demethylase 1 (LSD1) reportedly has therapeutic effects on a variety of tumors. This study explored the therapeutic effect of LSD1 inhibition on glioblastoma cell lines and the possible underlying mec...

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Detalles Bibliográficos
Autores principales: Li, Wei, Huang, Bai-sheng, Xiong, Yuan-yuan, Yang, Li-jian, Wu, Li-xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764814/
https://www.ncbi.nlm.nih.gov/pubmed/35042538
http://dx.doi.org/10.1186/s12935-021-02434-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764814/
https://www.ncbi.nlm.nih.gov/pubmed/35042538
http://dx.doi.org/10.1186/s12935-021-02434-5

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