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4,5-Dimethoxycanthin-6-one is a novel LSD1 inhibitor that inhibits proliferation of glioblastoma cells and induces apoptosis and pyroptosis

BACKGROUND: Glioblastoma is one of the most common fatal intracranial malignancies. Lysine-specific demethylase 1 (LSD1) reportedly has therapeutic effects on a variety of tumors. This study explored the therapeutic effect of LSD1 inhibition on glioblastoma cell lines and the possible underlying mec...

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Detalles Bibliográficos
Autores principales:	Li, Wei, Huang, Bai-sheng, Xiong, Yuan-yuan, Yang, Li-jian, Wu, Li-xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764814/ https://www.ncbi.nlm.nih.gov/pubmed/35042538 http://dx.doi.org/10.1186/s12935-021-02434-5

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