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Impact of sleep patterns upon female neuroendocrinology and reproductive outcomes: a comprehensive review

Sleep is vital to human bodily function. Growing evidence indicates that sleep deprivation, disruption, dysrhythmia, and disorders are associated with impaired reproductive function and poor clinical outcomes in women. These associations are largely mediated by molecular-genetic and hormonal pathway...

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Autores principales: Beroukhim, Gabriela, Esencan, Ecem, Seifer, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764829/
https://www.ncbi.nlm.nih.gov/pubmed/35042515
http://dx.doi.org/10.1186/s12958-022-00889-3
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author Beroukhim, Gabriela
Esencan, Ecem
Seifer, David B.
author_facet Beroukhim, Gabriela
Esencan, Ecem
Seifer, David B.
author_sort Beroukhim, Gabriela
collection PubMed
description Sleep is vital to human bodily function. Growing evidence indicates that sleep deprivation, disruption, dysrhythmia, and disorders are associated with impaired reproductive function and poor clinical outcomes in women. These associations are largely mediated by molecular-genetic and hormonal pathways, which are crucial for the complex and time sensitive processes of hormone synthesis/secretion, folliculogenesis, ovulation, fertilization, implantation, and menstruation. Pathologic sleep patterns are closely linked to menstrual irregularity, polycystic ovarian syndrome, premature ovarian insufficiency, sub/infertility, and early pregnancy loss. Measures of success with assisted reproductive technology are also lower among women who engage in shift work, or experience sleep disruption or short sleep duration. Extremes of sleep duration, poor sleep quality, sleep disordered breathing, and shift work are also associated with several harmful conditions in pregnancy, including gestational diabetes and hypertensive disorders. While accumulating evidence implicates pathologic sleep patterns in impaired reproductive function and poor reproductive outcomes, additional research is needed to determine causality and propose therapeutic interventions.
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spelling pubmed-87648292022-01-19 Impact of sleep patterns upon female neuroendocrinology and reproductive outcomes: a comprehensive review Beroukhim, Gabriela Esencan, Ecem Seifer, David B. Reprod Biol Endocrinol Review Sleep is vital to human bodily function. Growing evidence indicates that sleep deprivation, disruption, dysrhythmia, and disorders are associated with impaired reproductive function and poor clinical outcomes in women. These associations are largely mediated by molecular-genetic and hormonal pathways, which are crucial for the complex and time sensitive processes of hormone synthesis/secretion, folliculogenesis, ovulation, fertilization, implantation, and menstruation. Pathologic sleep patterns are closely linked to menstrual irregularity, polycystic ovarian syndrome, premature ovarian insufficiency, sub/infertility, and early pregnancy loss. Measures of success with assisted reproductive technology are also lower among women who engage in shift work, or experience sleep disruption or short sleep duration. Extremes of sleep duration, poor sleep quality, sleep disordered breathing, and shift work are also associated with several harmful conditions in pregnancy, including gestational diabetes and hypertensive disorders. While accumulating evidence implicates pathologic sleep patterns in impaired reproductive function and poor reproductive outcomes, additional research is needed to determine causality and propose therapeutic interventions. BioMed Central 2022-01-18 /pmc/articles/PMC8764829/ /pubmed/35042515 http://dx.doi.org/10.1186/s12958-022-00889-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Beroukhim, Gabriela
Esencan, Ecem
Seifer, David B.
Impact of sleep patterns upon female neuroendocrinology and reproductive outcomes: a comprehensive review
title Impact of sleep patterns upon female neuroendocrinology and reproductive outcomes: a comprehensive review
title_full Impact of sleep patterns upon female neuroendocrinology and reproductive outcomes: a comprehensive review
title_fullStr Impact of sleep patterns upon female neuroendocrinology and reproductive outcomes: a comprehensive review
title_full_unstemmed Impact of sleep patterns upon female neuroendocrinology and reproductive outcomes: a comprehensive review
title_short Impact of sleep patterns upon female neuroendocrinology and reproductive outcomes: a comprehensive review
title_sort impact of sleep patterns upon female neuroendocrinology and reproductive outcomes: a comprehensive review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764829/
https://www.ncbi.nlm.nih.gov/pubmed/35042515
http://dx.doi.org/10.1186/s12958-022-00889-3
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