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Metabolic comorbidities of psoriasis (Review)
Psoriasis is a chronic inflammatory and immune-mediated condition, which is no longer considered as being limited to the skin, but may affect the entire body. Epidemiological studies have shown that certain disorders, including obesity, diabetes, liver abnormalities, elevated lipid levels in the blo...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764894/ https://www.ncbi.nlm.nih.gov/pubmed/35069860 http://dx.doi.org/10.3892/etm.2021.11102 |
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author | Branisteanu, Daciana Elena Pirvulescu, Ruxandra Angela Spinu, Alina Elena Porumb, Elena Andrese Cojocaru, Mihaela Nicolescu, Alin Codrut Branisteanu, Daniel Constantin Branisteanu, Catalina Ioana Dimitriu, Andreea Alexa, Anisia Iuliana Toader, Mihaela Paula |
author_facet | Branisteanu, Daciana Elena Pirvulescu, Ruxandra Angela Spinu, Alina Elena Porumb, Elena Andrese Cojocaru, Mihaela Nicolescu, Alin Codrut Branisteanu, Daniel Constantin Branisteanu, Catalina Ioana Dimitriu, Andreea Alexa, Anisia Iuliana Toader, Mihaela Paula |
author_sort | Branisteanu, Daciana Elena |
collection | PubMed |
description | Psoriasis is a chronic inflammatory and immune-mediated condition, which is no longer considered as being limited to the skin, but may affect the entire body. Epidemiological studies have shown that certain disorders, including obesity, diabetes, liver abnormalities, elevated lipid levels in the blood and metabolic syndrome, may occur more frequently in patients with psoriasis compared with the general population. As psoriasis is a chronic disease, the frequently associated comorbidities must be identified early to ensure timely treatment and, possibly, their prevention. Comorbidities often manifest clinically 1-2 years after the onset of psoriasis and are commonly seen in patients with severe forms of the disease. The association between psoriasis and its comorbidities is not coincidental, but rather based on common pathophysiological mechanisms and risk factors that underlie the increased frequency of comorbidities in patients with psoriasis. The aim of the present review was to emphasize the important role of dermatologists in the early recognition of comorbidities in patients with psoriasis, with a focus on metabolic comorbidities, precisely because the dermatologists are usually the first medical contact due to the predominance of skin lesions. Therefore, these specialists have the responsibility to inform patients on the association between psoriasis and possible multiple comorbidities, devise prevention and treatment plans, or even redirect patients to other specialists. |
format | Online Article Text |
id | pubmed-8764894 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-87648942022-01-20 Metabolic comorbidities of psoriasis (Review) Branisteanu, Daciana Elena Pirvulescu, Ruxandra Angela Spinu, Alina Elena Porumb, Elena Andrese Cojocaru, Mihaela Nicolescu, Alin Codrut Branisteanu, Daniel Constantin Branisteanu, Catalina Ioana Dimitriu, Andreea Alexa, Anisia Iuliana Toader, Mihaela Paula Exp Ther Med Review Psoriasis is a chronic inflammatory and immune-mediated condition, which is no longer considered as being limited to the skin, but may affect the entire body. Epidemiological studies have shown that certain disorders, including obesity, diabetes, liver abnormalities, elevated lipid levels in the blood and metabolic syndrome, may occur more frequently in patients with psoriasis compared with the general population. As psoriasis is a chronic disease, the frequently associated comorbidities must be identified early to ensure timely treatment and, possibly, their prevention. Comorbidities often manifest clinically 1-2 years after the onset of psoriasis and are commonly seen in patients with severe forms of the disease. The association between psoriasis and its comorbidities is not coincidental, but rather based on common pathophysiological mechanisms and risk factors that underlie the increased frequency of comorbidities in patients with psoriasis. The aim of the present review was to emphasize the important role of dermatologists in the early recognition of comorbidities in patients with psoriasis, with a focus on metabolic comorbidities, precisely because the dermatologists are usually the first medical contact due to the predominance of skin lesions. Therefore, these specialists have the responsibility to inform patients on the association between psoriasis and possible multiple comorbidities, devise prevention and treatment plans, or even redirect patients to other specialists. D.A. Spandidos 2022-02 2021-12-28 /pmc/articles/PMC8764894/ /pubmed/35069860 http://dx.doi.org/10.3892/etm.2021.11102 Text en Copyright: © Branisteanu et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Review Branisteanu, Daciana Elena Pirvulescu, Ruxandra Angela Spinu, Alina Elena Porumb, Elena Andrese Cojocaru, Mihaela Nicolescu, Alin Codrut Branisteanu, Daniel Constantin Branisteanu, Catalina Ioana Dimitriu, Andreea Alexa, Anisia Iuliana Toader, Mihaela Paula Metabolic comorbidities of psoriasis (Review) |
title | Metabolic comorbidities of psoriasis (Review) |
title_full | Metabolic comorbidities of psoriasis (Review) |
title_fullStr | Metabolic comorbidities of psoriasis (Review) |
title_full_unstemmed | Metabolic comorbidities of psoriasis (Review) |
title_short | Metabolic comorbidities of psoriasis (Review) |
title_sort | metabolic comorbidities of psoriasis (review) |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764894/ https://www.ncbi.nlm.nih.gov/pubmed/35069860 http://dx.doi.org/10.3892/etm.2021.11102 |
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