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Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts

A key unknown of the functional space in tumor immunity is whether CD4 T cells depend on intratumoral MHCII cancer antigen recognition. MHCII-expressing, antigen-presenting cancer-associated fibroblasts (apCAFs) have been found in breast and pancreatic tumors and are considered to be immunosuppressi...

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Detalles Bibliográficos
Autores principales:	Kerdidani, Dimitra, Aerakis, Emmanouil, Verrou, Kleio-Maria, Angelidis, Ilias, Douka, Katerina, Maniou, Maria-Anna, Stamoulis, Petros, Goudevenou, Katerina, Prados, Alejandro, Tzaferis, Christos, Ntafis, Vasileios, Vamvakaris, Ioannis, Kaniaris, Evangelos, Vachlas, Konstantinos, Sepsas, Evangelos, Koutsopoulos, Anastasios, Potaris, Konstantinos, Tsoumakidou, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764966/ https://www.ncbi.nlm.nih.gov/pubmed/35029648 http://dx.doi.org/10.1084/jem.20210815

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