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Sangivamycin is highly effective against SARS-CoV-2 in vitro and has favorable drug properties
Sangivamycin is a nucleoside analog that is well tolerated by humans and broadly active against phylogenetically distinct viruses, including arenaviruses, filoviruses, and orthopoxviruses. Here, we show that sangivamycin is a potent antiviral against multiple variants of replicative severe acute res...
Autores principales: | Bennett, Ryan P., Postnikova, Elena N., Eaton, Brett P., Cai, Yingyun, Yu, Shuiqing, Smith, Charles O., Liang, Janie, Zhou, Huanying, Kocher, Gregory A., Murphy, Michael J., Smith, Harold C., Kuhn, Jens H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765048/ https://www.ncbi.nlm.nih.gov/pubmed/34807849 http://dx.doi.org/10.1172/jci.insight.153165 |
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