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Soluble PD-L1 works as a decoy in lung cancer immunotherapy via alternative polyadenylation
Immune checkpoint therapy targeting the PD-1/PD-L1 axis is a potentially novel development in anticancer therapy and has been applied to clinical medicine. However, there are still some problems, including a relatively low response rate, innate mechanisms of resistance against immune checkpoint bloc...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765052/ https://www.ncbi.nlm.nih.gov/pubmed/34874919 http://dx.doi.org/10.1172/jci.insight.153323 |